DRD2 Gene: Insilico Approach for Functional Protein Partners and Regulatory Pathways Analysis

Abstract

Bioinformatics methodologies have made possible to profile the global composition of tissue or organelle at specific time point or under particular developmental or disease state. Extensive research into the genomics of neuropsychiatric diseases such as schizophrenia - a chronic brain disorder that may develop from a combination of multiple factors and affects approximately 1% people worldwide has revealed the importance of DRD2 gene in the development of disease. The study depicts the computational analysis of DRD2 gene exploring molecular networks of interacting targets by STRING’s database, KEGG and Reactome pathways and BioGrid databases- current bioinformatics tools that may provide insights into the biological processes underlying schizophrenia.