Identification and Isolation of fungus from food and determination of its antibacterial activity
Keywords:Agar well diffusion, , Pharmacological activity, Secondary metabolites
The issue of drug resistant pathogens is the most well-known issue now days. Irresistible and parasitic infections are still the second driving reason for death. This is the major cause to examine their antibacterial activity. The antimicrobial compounds produced by fungus naturally are the most vital source of their discovery. Parasites are easy and valuable source with the great pharmaceutical potential. This study was led to explore that whether the infectious metabolites have ability to repress or execute the human pathogenic microscopic organisms. The parasitic metabolites were segregated from Aspergillus niger , Aspergillus fumigatus , Aspergillus flavus , Rhizopus and Penicillium and check their antibacterial action against human pathogenic microorganisms, for example, Staphylococcus aureus, Streptococcus pyogenes and Pseudomonas aeroginosa. Zone of inhibition were measured by agar well diffusion method and pharmacological activity analyzed by qualitative test, for example, glycoside, alkaloid and tannins test. The results demonstrated that just Aspergillus fumigatus have pharmacological activity and it give zone of restraint against human pathogenic microbes. Other fungi for example, Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger, Rhizopus and Penicillium did not give any zone of inhibition against Staphylococcus aureus, Streptococcus pyogenes and Pseudomonas aeroginosa. Aspergillus fumigatus metabolites can be use for the preparation of antibiotic.