Effect of Azadirachta indica extract on phagocytic activity against the common clinical pathogen

  • Rimsha Saeed Jinnah University for Women, Karachi Pakistan.
  • Amna Shafiq Jinnah University for Women, Karachi Pakistan.

Abstract

Antimicrobial resistance exhibit by pathogenic microorganisms has encouraged more biocompatible and eco-friendly approaches to screening of herbs for their prospective antibiotic activity to manage and control infectious diseases. Herbal plants play a paramount role in the complementary medicines worldwide because of their many health benefits with no side effects. The objective of this study was to determine in vitro effect of Azadirachta indica (neem) on phagocytic activity against the common clinical pathogen Staphylococcus aureus. The phagocytic activity was determined by employing slide method. In this method, number of ingested cells was found to be 60 out of 100 after 1.5 hour incubation of blood sample with Staphylococcus aureus and Azadirachta indica. Azadirachta indica showed enhanced phagocytic activity as compared to control blood sample without the herb. This suggests that diet or drug supplemented with Azadirachta indica (Neem) is likely to augment the immune system and reduce the growth of pathogenic bacteria like Staphylococcus aureus.

Author Biographies

Rimsha Saeed, Jinnah University for Women, Karachi Pakistan.

Department of Microbiology

Amna Shafiq, Jinnah University for Women, Karachi Pakistan.

Department of Microbiology

Published
2017-12-12
How to Cite
SAEED, Rimsha; SHAFIQ, Amna. Effect of Azadirachta indica extract on phagocytic activity against the common clinical pathogen. RADS Journal of Biological Research & Applied Sciences, [S.l.], v. 8, n. 2, p. 42-45, dec. 2017. ISSN 2521-8573. Available at: <http://jbas.juw.edu.pk/index.php/JBAS/article/view/99>. Date accessed: 16 aug. 2018.